Description

Poly Oxyl 40 Hydrogenated Castor Oil is almost odour and tasteless white transparent thick liquid.

Poly Oxyl 40 Hydrogenated Castor Oil is chemically polyoxyl 40 hydrogenated castor oil confirms to USP/NF/ EP specification.

Typical Specifications

¤ Color : White / transparent
¤ Consistency : thick liquid at 300c
¤ Congealing temperature : 200c to 300c
¤ Hydroxyl value : 60 - 80
¤ Iodine value : NMT 2%
¤ Saponification value : 45 - 69
¤ pH (10% aqueous soln.) : 6 - 7
¤ Viscosity : 20 - 40 maps
¤ Refractive index at 200c : 1.45 + 0.004
¤ Water : NMT 3%
¤ Residue on ignition : NMT 0.3%
¤ Heavy Metals : NMT 0.001%
¤ Acid value : NMT 2%
¤ Solubility : soluble in water, ethanol 2-propanol, ethyl acetate, n-propanol, chloroform, carbon tetrachloride, tolune & xylene.

Advantages

¤ Versatility
¤ Tasteless
¤ Colourless and transparent
¤ Reduces consumption
¤ Stable over a wide temperature range
¤ Self shining
¤ Highly hydrophilic
¤ Improves foam stability
¤ pH independent
¤ Elegant
¤ Smooth and luxurious feeling
¤ Biodegradable and ecofriendly

Replacement For

Poly Oxyl 40 Hydrogenated Castor Oil is replacement for Cremophor RH40, Crysmer RH-40 and Tween 80.

Typical Applications

¤ Solubilizer
Poly Oxyl 40 Hydrogenated Castor Oil improves water solubility of major water insoluble products. Improves compatibility of incompatible ingredients.

¤ Solubilizing method for vitamis
Poly Oxyl 40 Hydrogenated Castor Oil is almost odourless and tasteless. It ca be added to oral and topical applications of vitamin A, D, E and K type form.

¤ Formulation
Aqueous vitamin A palmitate solution (150 000 l.u/ml)
Vitamin A palmitate : 1.7 million L.U/8.8g.
Poly Oxyl 40 Hydrogenated Castor Oil : 25.0 g.
Water : add 100 ml.

Mix vitamin with Poly Oxyl 40 Hydrogenated Castor Oil and heat up to 600 to 650C. Heat water at the same temperature. With stirring ad water in mixtue of Poly Oxyl 40 Hydrogenated Castor Oil and vitamin. As a result of hydration, the viscosity will increase after addition of around 50% water. Full addition of water will decrease the viscosity up to required level. Quick addition of first 50% water can make the formulation opalescent. Slow addition of water is preffered.

¤ Solubilizing of Pharma Ingrediants
Poly Oxyl 40 Hydrogenated Castor Oilsolubilizes various hydrophobic substances in aqueous solutions and make solutions clear.
Hexachlorocyclohexane      Miconazole
Hexedine                          Gramicidin
Levomepromazine             Eucalyptol
Thiopental
Benzocaine                       Oil of anise
Clotrimazole                     Oil of sage
Diazepam.

¤ Foam Stabilizer
Poly Oxyl 40 Hydrogenated Castor Oil has little tendency to foaming. But it works excellent when foaming agents are added into the formulations. It works as foam booster and foam stabilizer. Poly Oxyl 40 Hydrogenated Castor Oil is preferable in shaving gel, hand wash gel, tooth paste and similar type of cleaning and toiletories, formulations. To reduce or eliminate the foam add small quantity of polypropylene glycol 2000 or simethecone.

¤ Emulsifier
Poly Oxyl 40 Hydrogenated Castor Oil is excellent versatile emulsifying agent. It will emulsify major hydrophobic substances like fatty acids, fatty alcohols, mineral oils.

¤ Moisturizer
Poly Oxyl 40 Hydrogenated Castor Oil improves moisturizing effect. It also improves soft feeling.

¤ Film Former
Poly Oxyl 40 Hydrogenated Castor Oil improves film foaming capability and flow properties.
Poly Oxyl 40 Hydrogenated Castor Oil is most preferred in Cream, Lotion, Lipstick etc; to improve film forming.

¤ Transparency Improvement
Poly Oxyl 40 Hydrogenated Castor Oilsolubilize insoluble oily substances in aqueous system. It improves transparency with shining. In cosmetic formulations, impacting elegance appearance in cosmetic products such as shaving gel, hair styling gel, hand wash gel. In Pharmaceutical syrup formulations it improves transparency.

¤ Volatility Retardment
Poly Oxyl 40 Hydrogenated Castor Oil retards volatilities of volatile solvents. It can be used for high volatile products like after shave perfumes to retain its effect for longer period.

¤ Masking Agent
Poly Oxyl 40 Hydrogenated Castor Oil masks upleasant taste and odour of typical volatile solvents like pharma syrup containing alcohols.

¤ Adhesion Reducer
Poly Oxyl 40 Hydrogenated Castor Oil reduces adhesion and chipping properties of oils. It gives smooth feeling on application like in all pharma, cosmetic creams, and lotions, hair oil, etc.

¤ Aerosol Formulations
Poly Oxyl 40 Hydrogenated Castor Oil improves solubility of the propellant in aerosols in aqueous phase.

Stability

Poly Oxyl 40 Hydrogenated Castor Oil is chemically highly stable product. Prolonged exposure to heat can cause physical separation into liquid and solid phase. At normal temperature it can be easily restored to original form by homogenization.

Poly Oxyl 40 Hydrogenated Castor Oil is stable in aqueous solutions and alcohol base aqueous solutions. Avoid use of strong bases and acids in formulations with Poly Oxyl 40 Hydrogenated Castor Oil as it may be Saponified.

Aqueous Poly Oxyl 40 Hydrogenated Castor Oil solutions can be sterilized by heating up to 1200C. pH may decrease slightly. In case of separation, slight agitation will remake the solution.

In aqueous solutions, add preservatives in requisite concentrations. The concentration should be determined by test. Poly Oxyl 40 Hydrogenated Castor Oil is largely immune to the salts of hard water.

Compatibility

With skin and mucous membranes : Swab tests have demonstrated that Poly Oxyl 40 Hydrogenated Castor Oil is compatible with human skin.


Sensitization

Poly Oxyl 40 Hydrogenated Castor Oil solutions of 20% and 50% concentration in acetone were brushed ten times on the skin of guinea pigs. They did not cause any sensitization of the skin.

Toxicity

Acute and chronic toxicity test in animals have shown Poly Oxyl 40 Hydrogenated Castor Oil is essentially non-toxic and non-irritant material.

Shelf Life

At least 2 years at room temperature (300C)

Packing

5 kgs., 20 kgs., & 50 kgs., in Plastic Carboys.