  |
Manufacturer
& Exporter of Binding Agent, Lubricants, Solublisers, Coatings,
Disintegrant & Super Disintegrant. |
Taste
Making Resins for Norfloxacin
.. Taste Masking Agent - 104Taste Masking Agent
- 104 is derived from crosslinked polymer of Methacrylic acid. Taste Masking
Agent - 104 has carboxylic acid functionally which is enables its use as a
TASTE MASKING AGENT, while the cross linked porous nature
makes its suitable as a
SUSTAIN RELEASE AGENT.
Specifications
The Physical & Chemical properties are as under :
| ..
Physical Properties |
| Appearance |
White to off white
flowing powder. |
| Solubility |
Insoluble in water and
common solvents. |
| Moisture Content |
10% max. |
| Particle Size |
1% max retained on 100
BSS and
70% min passing through 200 BSS |
| ..
Chemical Properties |
| Polymeric Functional
Group |
Carboxylic Acid |
| Sodium Content |
0.2% max. |
| Iron Content as Fe |
100 ppm max |
| Heavy Metals as Pb |
10 ppm max |
| Arsenic Content as As |
3 ppm max. |
Applications
1. Taste Masking Agent : A drug polymer adduct can
be synthesized due to the ionic bonding between the bitter drug and the
polymer thus masking the objectionable bitter taste of the drug. Since the
polymer drug adduct so formed is tasteless in the mouth, but it dissociates
in the acidic pH of the stomach, the bio availability of the drug is not
effected.
Examples : Norfloxacin, Ofloxacin
2.
Sustain Release of Nicotine : The crosslinked porous polymer
facilitates sustain release of nicotine.
Toxicity
Taste Masking Agent - 104 is high molecular weight polymer so can't be
absorbed by body tissued & is safe for human consumption. It has no any
physiological action at recommended dosage & it is non-toxic.
Storage
Store in tightly container. Keep away from moisture. If moisture is
absorbed, dry at 900C to 1000C to remove moisture content below 10%.
Packing
5 kg, 20 kg, in Corrugated Box.
Note : Application
notes and MSDS sheet can be made available on request.
.. Taste Masking Rosin - 134Taste Masking Rosin
- 134 is derived from crosslinked polymer of acrylic acid and has a K +
ionic form. Taste Masking Rosin - 134 is a very high purity polymer finding
use in pharmaceutical formulations for
TASTE MASING of certain
drugs, particularly B-lactum antibiotics.
Specifications
The Physical & Chemical properties are as under :
| ..
Physical Properties |
| Appearance |
White off white free
flowing powder. |
| Solubility |
Insoluble in water and
common solvents |
| Moisture Content |
10% max. |
| Particle Size |
1% max retained on 100
BSS and
70% min passing through 200 BSS |
| ..
Chemical Properties |
| Polymeric Functional
Group |
Carboxylic Acid |
| Potassium content |
Potassium content 20.6 to
25.1% |
| Sodium Content |
0.2% max. |
| Iron Content as Fe |
100 ppm max |
| Heavy Metals as Pb |
10 ppm max |
| Arsenic Content as As |
3 ppm max. |
Applications
1. Taste Masking Agent : Taste Masking Rosin - 134
forms complex with drug & mask it's bitter taste. This complex formed
does not dissociate in saliva pH but, dissociate in acidic pH of stomach.
Thus this complex is tasteless without affecting its bio availability. This
technique helps to formulate palatable & chewable tablets, dispersible
tablet & suspensions of bitter taste drugs.
Examples :
Chloroquine Phosphate, Ciprofloxacin HCL, Chloroquine Sulphate,
Dextromethorphan Hydrobromide, Metoclopramide Hydrochloride.
Toxicity
Taste Masking Rosin - 134 is high molecular weight polymer so can't be
absorbed by body tissues & is safe for human consumption. It has no any
physiological action at recommended dosage & it is non-toxic.
Storage
Store in tightly closed container. Keep away from moisture. If moisture
is absorbed dry at 900C to 1000C to remove moisture content below 10%.
Packing
5 kg, 20 kg, in Corrugated Box.
about
us
